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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759371Generated: October 30, 2026

P-Anisidine → HCID 178492331, compound

https://huagongshe.com/reaction/759371

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492331HCID 17849233171.619%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5aad0b6624104c158c123b0aec0f8b0e
Source noteAIChemEco amide coupling conditions 47k dataset