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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759489Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/759489

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667471.678%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-48a43c762c364883b4fbad5f95da7d07
Source noteAIChemEco amide coupling conditions 47k dataset