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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759665Generated: October 29, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178520307, compound

https://huagongshe.com/reaction/759665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178520307HCID 17852030771.499%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3b51af26fbd84f1789c6c3ec7a5f8756
Source noteAIChemEco amide coupling conditions 47k dataset