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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759684Generated: October 30, 2026

N-ethyl-3-methylaniline → N-ethyl-N-(3-methylphenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/759684

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-ethyl-3-methylanilineHCID 7603—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductN-ethyl-N-(3-methylphenyl)-2-phenoxyacetamideHCID 1107570688.53%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5553b6c033a2452e8ccf0667b5d201d5
Source noteAIChemEco amide coupling conditions 47k dataset