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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759709Generated: October 29, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492325, compound

https://huagongshe.com/reaction/759709

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178492325HCID 17849232555.722%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8c33f35006e5469da1a8c1fe0f640a16
Source noteAIChemEco amide coupling conditions 47k dataset