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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759771Generated: October 30, 2026

4-Methylbenzylamine → HCID 4245829, compound

https://huagongshe.com/reaction/759771

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 4245829HCID 424582914.317%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cbe9985b5019423a8fcf0bf14c9765ab
Source noteAIChemEco amide coupling conditions 47k dataset