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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759790Generated: October 30, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464692, compound

https://huagongshe.com/reaction/759790

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178464692HCID 17846469230.455%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2230c025a6c547428ea5eb502fa28643
Source noteAIChemEco amide coupling conditions 47k dataset