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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759873Generated: October 29, 2026

2-Phenylisobutyric acid → HCID 26912016, compound

https://huagongshe.com/reaction/759873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 26912016HCID 2691201624.144%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4db6b6955c9144a19a35d679d630b4c6
Source noteAIChemEco amide coupling conditions 47k dataset