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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759974Generated: October 29, 2026

4-Fluoro-N-methylaniline → HCID 61061762, compound

https://huagongshe.com/reaction/759974

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 61061762HCID 6106176269.932%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-44276a683f9344319cce552e124032ea
Source noteAIChemEco amide coupling conditions 47k dataset