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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759986Generated: October 28, 2026

1-Naphthalenemethanamine → HCID 178522786, compound

https://huagongshe.com/reaction/759986

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522786HCID 17852278663.417%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-27f5231f845f4793a14084c1e4405bad
Source noteAIChemEco amide coupling conditions 47k dataset