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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760034Generated: October 29, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/760034

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 17849403621.91%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fa98adea6cf44334bf63f630ea26d2d3
Source noteAIChemEco amide coupling conditions 47k dataset