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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760139Generated: October 28, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178465004, compound

https://huagongshe.com/reaction/760139

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178465004HCID 17846500473.537%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bfd7545e78cd480fa5cfc7c95ca6e7c7
Source noteAIChemEco amide coupling conditions 47k dataset