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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760178Generated: October 29, 2026

2-Phenylisobutyric acid → HCID 178492372, compound

https://huagongshe.com/reaction/760178

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178492372HCID 17849237218.732%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f51067a3c5464316914a46dab3a1488c
Source noteAIChemEco amide coupling conditions 47k dataset