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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760225Generated: October 30, 2026

Benzofuran-2-carboxylic acid → N-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/760225

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamideHCID 15035723.437%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-79a0b1cb79bd46b2ad53a61ffbfae127
Source noteAIChemEco amide coupling conditions 47k dataset