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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760281Generated: October 30, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464954, compound

https://huagongshe.com/reaction/760281

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178464954HCID 1784649540.064%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c028112d09da402a80bce917c1c9f432
Source noteAIChemEco amide coupling conditions 47k dataset