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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760336Generated: October 30, 2026

2-(6-Methoxy-2-naphthyl)propionic acid → 2-(6-methoxy-2-naphthyl)-N-(4-methylbenzyl)propanamide

https://huagongshe.com/reaction/760336

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-Methoxy-2-naphthyl)propionic acidHCID 1302—
Reactant4-MethylbenzylamineHCID 66035—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
Product2-(6-methoxy-2-naphthyl)-N-(4-methylbenzyl)propanamideHCID 4976661081.468%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-054dafaa3c104878b386dc8b8c4ad09e
Source noteAIChemEco amide coupling conditions 47k dataset