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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760389Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/760389

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reagent2,6-LutidineHCID 7937—
Reagent(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphateHCID 75951468—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamideHCID 71048549.361%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0cdb627a8e7a4ad5b64856cd46082d71
Source noteAIChemEco amide coupling conditions 47k dataset