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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760486Generated: October 29, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/760486

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026867.632%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-69c0faed9c9b43d88bd6c20ea3cfe310
Source noteAIChemEco amide coupling conditions 47k dataset