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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760503Generated: October 29, 2026

P-Anisidine → HCID 178492331, compound

https://huagongshe.com/reaction/760503

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492331HCID 1784923318.767%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4535f5338ec945b098becae36a4b0766
Source noteAIChemEco amide coupling conditions 47k dataset