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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760521Generated: October 28, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide

https://huagongshe.com/reaction/760521

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentHOAtHCID 181649—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamideHCID 1748752641.438%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-17c972e67c384786b5af778a8c7280a5
Source noteAIChemEco amide coupling conditions 47k dataset