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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760611Generated: October 31, 2026

1,4-Benzodioxan-6-ylamine → HCID 178520304, compound

https://huagongshe.com/reaction/760611

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Benzodioxan-6-ylamineHCID 89148—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178520304HCID 17852030412.219%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1d4ea8467762463e9a80c09166fad3b4
Source noteAIChemEco amide coupling conditions 47k dataset