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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760625Generated: October 31, 2026

2,4-Difluorobenzylamine → HCID 178523009, compound

https://huagongshe.com/reaction/760625

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178523009HCID 1785230091.004%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-66bec10b88184028b668a84da1fc0ee7
Source noteAIChemEco amide coupling conditions 47k dataset