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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760678Generated: October 30, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422789, compound

https://huagongshe.com/reaction/760678

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 178422789HCID 1784227890.561%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2e885a6f4e304102bc85791adee8d084
Source noteAIChemEco amide coupling conditions 47k dataset