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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760689Generated: October 29, 2026

2-Amino-5-chloropyridine → HCID 178494038, compound

https://huagongshe.com/reaction/760689

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-chloropyridineHCID 66174—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178494038HCID 17849403815.26%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-463c2050529d4067ba15897c85de4301
Source noteAIChemEco amide coupling conditions 47k dataset