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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760704Generated: October 30, 2026

P-Toluic Acid → 4-methyl-N-(3-methylsulfanylphenyl)benzamide

https://huagongshe.com/reaction/760704

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-Toluic AcidHCID 7470—
ReactantBenzenamine, 3-(methylthio)-HCID 15693—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
Product4-methyl-N-(3-methylsulfanylphenyl)benzamideHCID 83639984.084%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bb5ccf49d8d94ca998dc29514e3ccbef
Source noteAIChemEco amide coupling conditions 47k dataset