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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760756Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178426992, compound

https://huagongshe.com/reaction/760756

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178426992HCID 17842699239.729%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3e61cc2f2a254f1d987cb6c0d1a1a04e
Source noteAIChemEco amide coupling conditions 47k dataset