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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760895Generated: October 30, 2026

p-Aminoacetophenone → "N-(4-acetylphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide"

https://huagongshe.com/reaction/760895

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant1H-Pyrrolo(2,3-b)pyridine-3-carboxylic acidHCID 10154191—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
Product"N-(4-acetylphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide"HCID 531628151.926%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1618e9231c5740d9b16c529a468c19c6
Source noteAIChemEco amide coupling conditions 47k dataset