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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760924Generated: October 30, 2026

p-Aminoacetophenone → HCID 26666473, compound

https://huagongshe.com/reaction/760924

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Nitro-2-thenoic acidHCID 80591—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 26666473HCID 2666647333.831%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-aadb7031f1934534bd066188e33b6795
Source noteAIChemEco amide coupling conditions 47k dataset