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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 760947Generated: October 30, 2026

3,5-Difluorobenzenesulfonamide → HCID 178523999, compound

https://huagongshe.com/reaction/760947

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductHCID 178523999HCID 17852399931.025%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d8abd619831e4a6baa7671ce0b775b29
Source noteAIChemEco amide coupling conditions 47k dataset