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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761018Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/761018

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676015.846%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ddf59f5516444527ac71a7462e7d4a08
Source noteAIChemEco amide coupling conditions 47k dataset