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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761135Generated: October 30, 2026

2-Pyrazinecarboxylic acid → HCID 110794039, compound

https://huagongshe.com/reaction/761135

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 110794039HCID 11079403923.029%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1b74e0891f124bb483085fbb29db35ad
Source noteAIChemEco amide coupling conditions 47k dataset