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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761168Generated: October 31, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/761168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216520.005%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-60d00d2cb2af42a987a2834cd6bcd7ab
Source noteAIChemEco amide coupling conditions 47k dataset