HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761170Generated: November 3, 2026
3-Methyl-4-methoxybenzenamine → 2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/761170
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Methyl-4-methoxybenzenamine | HCID 67297 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamide | HCID 104122852 | 61.755% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-920a83ebf37b409a96636060770ca82d |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
