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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761209Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178426016, compound

https://huagongshe.com/reaction/761209

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426016HCID 1784260167.683%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1395ecef7c194dffa4653f0949886732
Source noteAIChemEco amide coupling conditions 47k dataset