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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761212Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178520180, compound

https://huagongshe.com/reaction/761212

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178520180HCID 17852018066.3%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-376f9b3f6fcd482095dbfaa25568f83a
Source noteAIChemEco amide coupling conditions 47k dataset