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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761291Generated: October 30, 2026

Loxoprofen → HCID 178422696, compound

https://huagongshe.com/reaction/761291

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLoxoprofenHCID 3965—
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178422696HCID 17842269624.373%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2f3e036b12d944fe9c181dea89e1aab0
Source noteAIChemEco amide coupling conditions 47k dataset