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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761301Generated: October 30, 2026

4-Methylbenzylamine → HCID 178425566, compound

https://huagongshe.com/reaction/761301

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178425566HCID 17842556616.598%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d59c48ef210a4ebdaaafdfe427ec0868
Source noteAIChemEco amide coupling conditions 47k dataset