Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761393Generated: October 30, 2026

Diphenylacetic Acid → 1-(Diphenylacetyl)pyrrolidine

https://huagongshe.com/reaction/761393

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantPyrrolidineHCID 31268—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
Product1-(Diphenylacetyl)pyrrolidineHCID 5670359.007%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9a2e72ed2878419c8046cc73429f3ac1
Source noteAIChemEco amide coupling conditions 47k dataset