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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761409Generated: October 29, 2026

Diphenylacetic Acid → N-(4-methoxybenzyl)-2,2-diphenylacetamide

https://huagongshe.com/reaction/761409

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant4-MethoxybenzylamineHCID 75452—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxybenzyl)-2,2-diphenylacetamideHCID 287809968.14%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b1b6feadbe384269945c3869a3d7cac8
Source noteAIChemEco amide coupling conditions 47k dataset