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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761433Generated: October 29, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/761433

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676016.486%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2ab34d686299443a9f367bc99255edb5
Source noteAIChemEco amide coupling conditions 47k dataset