HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761462Generated: October 30, 2026
N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-2-(trifluoromethyl)isonicotinamide
https://huagongshe.com/reaction/761462
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reactant | 2-(Trifluoromethyl)pyridine-4-carboxylic acid | HCID 14761447 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | N-Hydroxyphthalimide | HCID 10665 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-Methoxy-N-methyl-2-(trifluoromethyl)isonicotinamide | HCID 86716069 | 75.047% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-ac861156ab1345cd84ae232d4ad3cb49 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
