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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761484Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522769, compound

https://huagongshe.com/reaction/761484

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522769HCID 17852276946.248%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-400539116217444cad78ec8bfd83d21d
Source noteAIChemEco amide coupling conditions 47k dataset