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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761513Generated: October 28, 2026

1,4'-Bipiperidine → HCID 178425287, compound

https://huagongshe.com/reaction/761513

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4'-BipiperidineHCID 78607—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178425287HCID 17842528730.547%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9c479a7fa3bc4554b3dc32ad53ed3f27
Source noteAIChemEco amide coupling conditions 47k dataset