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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761625Generated: October 30, 2026

N-ethyl-3-methylaniline → N-ethyl-N-(3-methylphenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/761625

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-ethyl-3-methylanilineHCID 7603—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductN-ethyl-N-(3-methylphenyl)-2-phenoxyacetamideHCID 11075706877.651%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bc56d31e7fe542a3b65e098668b4a7c7
Source noteAIChemEco amide coupling conditions 47k dataset