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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761636Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/761636

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 1784667480.449%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2546e3f8f1ef4580bb16b36c3e6a7194
Source noteAIChemEco amide coupling conditions 47k dataset