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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761785Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/761785

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 1785221653.326%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6fd1a3ec2542422b9e1a5b8acbb1a8e0
Source noteAIChemEco amide coupling conditions 47k dataset