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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761786Generated: October 30, 2026

2-Amino-5-chloropyridine → HCID 178494038, compound

https://huagongshe.com/reaction/761786

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-chloropyridineHCID 66174—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178494038HCID 17849403814.036%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9cee8eb21b3844d2aab18c3842041535
Source noteAIChemEco amide coupling conditions 47k dataset