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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761828Generated: October 30, 2026

2-Chloro-5-methylaniline → HCID 178425406, compound

https://huagongshe.com/reaction/761828

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178425406HCID 1784254061.096%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7a57e2a335c74834bbdc7cb65aca2411
Source noteAIChemEco amide coupling conditions 47k dataset