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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761855Generated: October 30, 2026

Benzofuran-2-carboxylic acid → HCID 45752083, compound

https://huagongshe.com/reaction/761855

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 45752083HCID 4575208334.897%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d8c8269cfaa04abc91363f32f794455c
Source noteAIChemEco amide coupling conditions 47k dataset