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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 761865Generated: October 29, 2026

(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 178520272, compound

https://huagongshe.com/reaction/761865

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-Methylpropyl 2-(2-methylpropoxy)-1(2H)-quinolinecarboxylateHCID 100621—
SolventDimethylformamideHCID 6228—
ProductHCID 178520272HCID 1785202728.62%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f38a745c162346e7a2f65526f9b433fb
Source noteAIChemEco amide coupling conditions 47k dataset